Cat allergy in humans is an allergic reaction to cat glycoprotein Fel d 1 secreted by the cat’s sebaceous glands. Fel d 1 is mostly found in the cat’s skin and saliva.

An allergic reaction is a histamine reaction that is usually characterized by coughing, wheezing, chest tightening, itching, nasal congestion, rash, watering eyes, sneezing and similar symptoms.

These include red, itchy, watery eyes; nasal congestion; itchy nose; sneezing; difficulty breathing (dyspnea); chronic sore throat and/or scratchy throat; coughing, wheezing, or itchy skin. Some people reported elevation of the skin upon being scratched by a cat.