Anaphylaxis – the most dangerous allergic reaction

The most famous and dangerous allergic reaction is anaphylaxis. Anaphylaxis is a severe, whole-body allergic reaction. After an initial exposure (“sensitizing dose”) to a substance like bee sting toxin, the person’s immune system becomes sensitized to that allergen. On a subsequent exposure (“shocking dose”), an allergic reaction occurs. This reaction is sudden, severe, and involves the whole body.In cases of anaphylaxis systemic reactions occur in just minutes and are characterized by breathing difficulties and circulatory shock that can be avoided only through injections of adrenaline and cortisonici.

The events of anaphylactic shock are:

* the pressure drop
* paleness
* tachycardia
* sweating
* angioedema inland areas above
* difficulty breathing
until you reach the circulatory collapse and death.

Most common causes of anaphylaxis: heterologous serum (for example, the horse serum used in the treatment of the bite of snakes and spiders), enzymes inoculated for injecting (ie subcutaneously, intramuscularly and intravenously), blood products (such as blood transfusions ), The anaphylaxis can be triggered or worsened exercise. You can have anaphylactic reactions to the localized area of penetration of antigen: skin, nasal membranes, the gastrointestinal tract. Anaphylactoid reactions are clinically similar all’anafilassi but recognize different mechanisms.

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